Chemistry & Analytics

Our Chemistry and Analytics team has a vast experience in all fields of physical and analytical chemistry, and is involved in numerous Task forces, consortia and EU registration projects. Chemistry and analytics team support the Knoell Group in various regulatory programs like REACH and registrations of agrochemicals and biocides. Our chemical assessment starts with the physico-chemical hazard assessment and is followed up with a risk characterisation.

Our services in the fields of chemistry and analysis

For the purpose of these assessments we

  • evaluate all available data according to Klimisch et al. (1997) and prepare a data gap analysis
  • monitor studies for physico-chemical properties and spectral and analytical tests according to OECD guidelines, EC, CIPAC and EPA methods and GLP
  • give advice on test systems for difficult substances such as poorly soluble, metals, UVCBs
  • develop tailor-made testing and registration strategies for each substance, in accordance to Annex IV-XI of Regulation (EC) No 1907/2006
  • develop integrated testing strategy approaches with the help of available data, read across analogues (or category dataset), expert statements and/or QSAR
  • use various QSAR tools (e.g. EPISuite, SPARC, Chemprop) to predict the physical and chemical properties for various substance types
  • have significant experience in the evaluation of QSAR predictions from various models in respect of their applicability for the regulatory purposes
  • evaluate with use of e.g. OECD Toolbox the possibility of read across (analogue as well category approach), prepare the read across justification
  • determine the need for classification and labelling according to regulation (EC) No 1272/2008 (CLP)
  • prepare robust study summaries in IUCLID and also the endpoint summaries for the final Chemical safety assessment (CSA) and its associated report (CSR)
  • prepare the individual parts of REACH dossiers, inquiries for non phase-in substances, PPORD dossiers
  • offer consultancy in case of the substance identity for well defined substances as well as for various types of UVCB substances
  • prepare expert statements in case we think the tests are not required
  • handle submissions in REACH IT
Ángeles Rico Rico Managing Director
+34 91 112 60 80 +34 91 112 60 75 send mail

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